HealthyWayRx

The Top 10 Best-Selling Drugs in the US

The pharmaceutical industry continues to evolve, bringing innovative treatments to millions of Americans while driving significant economic growth. In 2024, the top-selling prescription drugs in the US reflect the diverse health challenges we face, from cancer and diabetes to autoimmune diseases and HIV. Below, we explore the leading medications, their uses, and what the booming drug discovery market means for patients like you.

The Top 10 Best-Selling Drugs in the US (2024)

Here’s a look at the top 10 prescription drugs by global sales in 2024, showcasing their importance in treating critical conditions:

  1. Keytruda (Merck) – $29.5 Billion
    Keytruda (pembrolizumab) is a groundbreaking immunotherapy used to treat various cancers, including lung, melanoma, and head and neck cancers. By boosting the immune system’s ability to fight cancer cells, it has become a cornerstone of modern oncology.
  2. Ozempic (Novo Nordisk) – $17.5 Billion
    Ozempic (semaglutide) is a game-changer for type 2 diabetes management and weight loss. Its ability to regulate blood sugar and support weight management has made it a household name, with demand soaring across the US.
  3. Dupixent (Sanofi/Regeneron) – $14.1 Billion
    Dupixent (dupilumab) treats chronic conditions like eczema, asthma, and nasal polyps. Its targeted approach to reducing inflammation has transformed the lives of patients with allergic and autoimmune disorders.
  4. Eliquis (Pfizer/BMS) – $13.3 Billion
    Eliquis (apixaban) is a blood thinner used to prevent strokes and blood clots in patients with atrial fibrillation or those recovering from surgery. Its safety profile and efficacy have made it a go-to anticoagulant.
  5. Biktarvy (Gilead) – $13.4 Billion
    Biktarvy is a single-tablet regimen for HIV treatment, offering patients a convenient and effective way to manage the virus. Its high efficacy and low side effects have solidified its place in HIV care.
  6. Skyrizi (AbbVie) – $11.7 Billion
    Skyrizi (risankizumab) is used for psoriasis and Crohn’s disease, providing relief from chronic inflammation. Its targeted mechanism makes it a preferred choice for autoimmune conditions.
  7. Darzalex (J&J) – $11.7 Billion
    Darzalex (daratumumab) is a vital treatment for multiple myeloma, a type of blood cancer. Its ability to target cancer cells directly has improved outcomes for patients with this challenging disease.
  8. Mounjaro (Eli Lilly) – $11.5 Billion
    Mounjaro (tirzepatide) is another standout for type 2 diabetes and weight management. Its dual action on blood sugar and appetite control has made it a strong competitor to Ozempic.
  9. Stelara (J&J) – $10.9 Billion
    Stelara (ustekinumab) treats psoriasis, psoriatic arthritis, and inflammatory bowel diseases like Crohn’s. Its versatility and long-lasting effects have earned it a loyal patient base.
  10. Trikafta (Vertex) – $10.2 Billion
    Trikafta (elexacaftor/tezacaftor/ivacaftor) is a transformative therapy for cystic fibrosis, targeting the genetic root of the disease. It has significantly improved lung function and quality of life for patients.

Why These Drugs Matter to You

These top-selling drugs address some of the most pressing health issues in the US, including cancer, diabetes, heart disease, and chronic inflammatory conditions. For patients, they represent hope, improved quality of life, and, in many cases, extended survival. At HealthyWayRx, we’re committed to making these medications accessible, whether through insurance navigation, affordable generics (where available), or patient assistance programs.

For example:

  • Cancer patients can access Keytruda and Darzalex, which are extending lives through cutting-edge science.
  • Diabetes and obesity patients benefit from Ozempic and Mounjaro, which offer dual benefits for blood sugar control and weight loss.
  • Chronic condition sufferers, such as those with eczema or psoriasis, find relief with Dupixent, Skyrizi, and Stelara.

Our pharmacy team is here to guide you through your treatment options, ensuring you understand your medication, its costs, and how to manage side effects.

The Future of Drug Discovery: What’s Next?

The global drug discovery services market is on a steep upward trajectory, projected to grow from $16.36 billion in 2025 to $27.23 billion by 2030, with a compound annual growth rate (CAGR) of 10.7%. This growth is fueled by advances in biotechnology, artificial intelligence, and personalized medicine, which are accelerating the development of new drugs.

What This Means for Patients

  • More Targeted Therapies: Expect drugs tailored to your genetic makeup, improving efficacy and reducing side effects.
  • Faster Drug Development: AI-driven research is shortening the time it takes to bring new medications to market.
  • Affordable Options: As innovation grows, generics and biosimilars for drugs like Keytruda or Stelara may become available, lowering costs.

At HealthyWayRx, we stay ahead of these trends to ensure you have access to the latest treatments. Whether it’s a new diabetes medication or a breakthrough cancer therapy, we’re your trusted partner in health.

How We Can Help

Navigating prescription medications can be overwhelming, especially with high-cost drugs like those listed above. Our pharmacy offers:

  • Competitive Pricing: We work to find the best prices and explore savings programs.
  • Home Delivery: Get your medications delivered safely and discreetly to your door.
  • Expert Consultations: Our pharmacists are here to answer questions about your treatment, from dosage to side effects.

Take Control of Your Health Today

The medications shaping 2024’s pharmaceutical landscape are transforming lives, and we’re here to ensure you can access them. Contact HealthyWayRx today to learn more about these treatments, check your prescription coverage, or schedule a consultation with our team. Together, we can build a healthier future.

Disclaimer: Always consult your healthcare provider before starting or changing medications. HealthyWayRx is not affiliated with the manufacturers of the drugs listed.